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Repurposed drug has promising efficacy in non-small cell lung cancer
UTSW-led clinical trial suggests broader use for selinexor in cancers with KRAS mutations
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Future of Thoracic Surgery
Inderpal Sarkaria, M.D., Chief of the Division of Thoracic Surgery, shares his optimism for the future of Thoracic Surgery at UT Southwestern.
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Director of Simmons Cancer Center, UTSW Pharmacology Chair elected to the National Academy of Medicine
Carlos L. Arteaga, M.D., and David Mangelsdorf, Ph.D., are UTSW’s 23rd and 24th members of the NAM, the most of any institution in Texas
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Latino enclaves in U.S. have less accessible health care
Study led by UTSW researcher describes socioeconomic challenges in culturally distinct neighborhoods for fastest-growing ethnic group
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UT Southwestern biochemist Zhijian ‘James’ Chen, Ph.D., earns prestigious Lasker Award
Dr. Chen’s discovery of cGAS, which triggers innate immunity, also honored with Germany’s top scientific prize
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Pathway tied to cancer-driving genome alterations identified
Understanding how chromosome shattering occurs could lead to strategies to overcome therapy resistance, UTSW study shows
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Widespread disparities exist in treating advanced cancers
Likelihood of patients receiving FDA-approved immunotherapies for late-stage kidney and bladder cancers linked to race, socioeconomic factors, facility type
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Basic Research: R01s – Drs. Todd Aguilera & You Zhang
Doctor Spotlights
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DARTBOARD Clinical Trial
DARTBOARD (STU2021-0401: A Prospective Randomized Phase II Study of Daily Adaptive Radiotherapy to Better Organ-at-Risk Doses in Head and Neck Cancer), an innovative, first-of-its-kind clinical trial, is now complete.
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Markerless Radiation Erases a Reminder and Improves Breast Cancer Therapy
Breast cancer almost always leaves its mark on patients. Along with surgical scars and changes in breast size and shape, medical tattoos or semi-permanent marker dots and lines were drawn on the patient’s chest to align radiotherapy beams, like checkpoints on a map.
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Upon Further RefleXion
The RefleXion X1 radiation treatment platform is the first to integrate PET/CT imaging with a medical linear accelerator. Using a PET signal identifying the tumor while also depicting its biology, RefleXion treats patients with unique biology-guided radiotherapy (BgRT). The UT Southwestern Department of Radiation Oncology is one of a handful of centers worldwide with this treatment capability.
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Upgrading HDR Brachytherapy
High-dose-rate (HDR) brachytherapy is a procedure where the patient receives a dose from a powerful radioactive source for a few minutes per treatment session, after which the source is removed. The radioactive source, stored in an afterloader unit, travels through special applicators that then deliver the dose to the site of the tumor.