PRAME induces genomic instability in uveal melanoma

February 12, 2024

A collage of images related to plaque brachytherapy for uveal melanoma

Professor and Chair of Ophthalmology J. William Harbour, M.D., and his research team discovered a novel function of PRAME [Preferentially Expressed Antigen in Melanoma] in uveal melanoma that may lead to new treatments.

Kurtenbach S, Sanchez MI, Kuznetsoff J, Rodriguez DA, Weich N, Dollar JJ, Cruz A, Kurtenbach S, Field MG, Durante MA, Decatur C, Sorouri M, Lai F, Yenisehirli G, Fang B, Shiekhattar R, Pelaez D, Correa ZM, Verdun RE, Harbour JW: PRAME induces genomic instability in uveal melanoma. Oncogene 2023 Nov 29.