UT Southwestern faculty from the Cecil H. and Ida Green Center for Reproductive Biology Sciences and the Department of Obstetrics and Gynecology have published a review of the essential role the uterine cervix plays in regulating fertility, maintaining pregnancy, remodeling in preparation for parturition, and protecting the reproductive tract from infection. This review published in the American Journal of Obstetrics and Gynecology highlights the importance of understanding molecular events that drive the multifunctional and temporally defined roles of the cervix as necessary for effectively treating infertility, reproductive tract infections, preterm birth, labor dystocia, and cervical cancer. This review focuses on insights gained from single-cell transcriptomic studies in human and mouse cervical tissue and highlights outstanding questions in the field.