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Driving Breakthrough Discoveries in Neurodegenerative Diseases
With its broad array of scientific talent, UT Southwestern's CAND is bringing exciting new advances to the study of Alzheimer’s disease and related disorders.
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After cornea damage, neurotization surgery can save patients’ vision
The cornea acts as a clear, protective dome over the eye, shielding it from damage and helping bend and focus light for proper vision. The cornea is also full of nerves; in fact, it is one of the most nerve-rich areas of the body.
Course
What’s New in GI 2024
What’s New in GI will provide attendees with practical information that can be applied today in their clinical practice. Discussions will include the latest updates on recognizing symptoms and using current data to establish diagnoses and formulate appropriate treatment plans for the management of gastrointestinal diseases. Several topics will be presented at this one-day symposium through lectures and Q&A session for UT Southwestern experts in the field of gastroenterology. This course is designed for gastroenterologists, GI surgeons, internal medicine physicians, family practice physicians, nurse practitioners, physician assistants and other health care providers with an interest in gastroenterology.
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The ILLUMINATE Study
Our clinical research team is conducting a Phase-2 clinical trial with a drug, pegsitacianine based on the fluorescent nanoparticles developed in our lab.
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Fluorescent nanoprobe lights the way to reducing spread of cancer cells
Healthy cells “eat” glucose, or sugar, to gain energy, divide, and heal themselves. Cancer cells, by comparison, consume glucose at a much higher volume to change their makeup, grow, and spread. The resulting byproduct is a tumor that secretes high levels of lactic acid, crippling the immune system’s defenses against the cancer.
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Using nanotechnology to attack cancer’s Achilles’ heel: acidity
Although cancers come in many forms, they all have a lower pH than normal tissue. Pharmacologist Jinming Gao, Ph.D., and head and neck surgeon Baran Sumer, M.D., have been working together for years on a pH-sensitive technology that can help surgeons more precisely excise tumors and help anti-tumor drugs get exactly where they need to be.
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Illuminating cancer: New pH threshold sensor improves cancer surgery
The high acidity of cancer cells yielded the clue that led to the development of a tool that significantly improves surgeons’ abilities to remove cancerous tissues. The invention by UT Southwestern researchers is a transistor-like threshold sensor that hones in on high pH, literally lighting up cancerous cells.
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UT Southwestern researchers seek to light up cancer cells so surgeons can better see where to cut
Baran Sumer, M.D. Professor and Chief of the Division of Head and Neck Oncology in UT Southwestern’s Department of Otolaryngology and a team of researchers from the Simmons Comprehensive Cancer Center developed a technology called a pH Nanosensor, an injection that seeks out cancerous areas in the body and causes them to light up.
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A transistor-like pH nanoprobe for tumour detection and image-guided surgery
UT Southwestern’s Baran Sumer, M.D., Professor and Chief of the Division of Head and Neck Oncology in the Department of Otolaryngology is among other researchers to report the design and performance of a fluorescent nanoprobe with transistor-like responses (transition pH?=?6.9) for the detection of deregulated pH, which drives many of the invasive properties of cancer.
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Gut microbiome offers clues to disparities in rectal cancer
UT Southwestern study identifies clustering of specific gut bacteria associated with race, ethnicity in patients
Video
Cancer Researchers are “Lighting Up” Cancer
Learn how cancer researchers are “lighting up” cancer by watching our Facebook Live chat with otolaryngologist Baran Sumer, M.D. Dr. Sumer is part of a team that developed a transistor-like nanosensor that can illuminate cancerous cells to assist surgeons.
Video
Factors Associated with Lymph Node Count in Head and Neck Cancer
Surgeons from the University of Texas Southwestern Medical Center carried-out a restrospective study on 247 patients with head and neck cancer to test whether age and undernutrition, factors known to negatively affect immune function, decreased lymph-node count in patients undergoing neck dissection.