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Assessing the Safety and Efficacy of High-Intensity Exercise Training for Patients with Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a common, inherited condition defined by abnormal thickening of the heart muscle.
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Effects of Tirzepatide on Ambulatory Blood Pressure and Heart Rate
Terzepatide is a new GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist that recently received FDA approval for treatment of Type 2 diabetes.
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Gene Editing Halts Damage in Mice After Heart Attacks in UT Southwestern Study
The figure shows cross-sections of mouse hearts with areas of damage in red. Treatment with virus-expressing CRISPR components reduces cardiac damage following ischemic injury.
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UTSW Researchers Discover Molecular Switch for Heart Regeneration
During embryonic growth and for a brief time after birth, mammals have a powerful ability to regenerate damaged heart cells. Shortly thereafter, however, this capability fades.
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UTSW Researchers Use DNA Analysis to Diagnose Subtypes of Heart Disease
The human heart is an intricate, complex organ and, like a car that starts sputtering, its function deteriorates for all sorts of reasons.
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Safer Imaging Technology for Complex Aortic Repairs Uses Light Instead of X-Rays
A new imaging device at UT Southwestern is making complex aortic repairs safer for patients and operating room staff by dramatically reducing their exposure to radiation.
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UT Southwestern team wins grand prize in American Heart Association Data Challenge
A team led by UT Southwestern Medical Center cardiologist Ambarish Pandey, M.D., was awarded the grand prize in the American Heart Association Heart Failure Data Challenge hosted by the American Heart Association and the Association of Black Cardiologists. The six-month data challenge asked researchers to test the relationships between heart failure and health disparities, social determinants of health, and structural determinants of health.
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First Successful Mini-Thoracotomy Bentall Using KONECT Valve
Cardiothoracic surgeon Neelan Doolabh, M.D., has performed more than 3,000 mini-thoracotomy cardiac surgeries through a two-inch intercostal incision. Now, Doolabh has achieved something even more challenging, performing a full bio-Bentall procedure using the same minimally invasive approach.
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Even with Regular Exercise, Astronaut’s Heart Left Smaller After a Year in Space
With NASA preparing to send humans to Mars in the 2030s, researchers are studying the physical effects of spending long periods in space. Now a new study by scientists at UT Southwestern shows that the heart of an astronaut who spent nearly a year aboard the International Space Station shrank, even with regular exercise, although it continued to function well.
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SGLT2 Inhibition in Acute Decompensated Heart Failure: Another Win for this Remarkable Class of Medications
The data as presented strongly support initiating SGLT2 inhibition during hospitalization for acute decompensated heart failure. Such an approach would be a change in the current standard of care for this large and ill population.
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Dominant Form of Heart Failure Caused by Metabolic-Immune Interaction, Review Article Suggests
The dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body’s response to metabolic stress and the immune system, according to a review article written by UT Southwestern researchers and colleagues.
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How ‘Diabetes Drugs’ Became Valuable Tools in Treating Heart Failure
As we pursue new therapies for heart failure, sometimes we stumble upon what the late Bob Ross referred to as “happy little accidents.” Sodium-glucose cotransporter 2 (SGLT2) inhibitor drugs for heart failure are one of my favorite research surprises.