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UT Southwestern research probes links between hippocampal hyperactivity in adolescence and development of psychosis
UT Southwestern faculty from the Department of Psychiatry and Neuroscience as well as the Dean of Simulation and Student Integration performed experiments providing striking evidence that may help to explain why psychosis typically emerges during adolescence and involves characteristic changes in activity within the brain’s hppocampus. In their paper appearing in Molecular Psychiatry, decades of research have indicated that abnormalities in the hippocampus may be linked not only with psychosis, but also with memory loss, depression, and PTSD-related anxiety.
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At UTSW, an innovative procedure offers new hope for amputees
Osseointegrated implants provide numerous benefits over conventional prostheses, surgeons say
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Electroconvulsive therapy or ketamine? Clinical factors affect outcomes
Characteristics of patients with treatment-resistant depression predict which therapy will be most beneficial, UTSW-led analysis reveals
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Popular diabetes/weight-loss drugs show additional benefit
Diabetes patients with related chronic kidney disease have better long-term outcomes on GLP1-RA therapies, UTSW researchers find
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Why do women have more trouble after knee injuries? UTSW model explains
Findings show impact of sex hormones, could lead to personalized therapy for joint trauma
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‘Heart in a box’ technology expands transplant capabilities
When a patient needs a heart transplant, time is of the essence. Two innovative technologies – one hot, one cold – can now keep the heart perfused outside the body, extending the organ’s viability for longer transports and expanding the pool of donor hearts.
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Preoperative immunotherapy could enhance breast cancer cure rates
Clinical trial shows new therapy holds promise for patients with subtype carrying high risk for metastasis
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Study reveals cellular recycling process key to human health
UTSW-led research team uses cryo-EM to show how protein receptors return to a cell’s surface
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Diagnosis Of Rare Cancer Led To Lifesaving Surgery and Access to Clinical Trial Treatment at UT Southwestern
With the expertise of Jayanthi Lea, M.D., a patient with low-grade serous ovarian carcinoma is now in remission.
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Shorter, safer protocol effectively treats triple-negative breast cancer
Adding radiation at start of treatment regimen produced results similar to current standard of care with fewer toxic side effects
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UTSW joins effort to create early screening for dementia
Ten U.S. health systems selected to develop programs to detect Alzheimer’s, other cognitive impairments
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Mood disorders drive feelings of cognitive decline in former college athletes
UT Southwestern study finds emotional health outweighs concussion history in shaping perceptions of impairment