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Even with Regular Exercise, Astronaut’s Heart Left Smaller After a Year in Space
With NASA preparing to send humans to Mars in the 2030s, researchers are studying the physical effects of spending long periods in space. Now a new study by scientists at UT Southwestern shows that the heart of an astronaut who spent nearly a year aboard the International Space Station shrank, even with regular exercise, although it continued to function well.
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SGLT2 Inhibition in Acute Decompensated Heart Failure: Another Win for this Remarkable Class of Medications
The data as presented strongly support initiating SGLT2 inhibition during hospitalization for acute decompensated heart failure. Such an approach would be a change in the current standard of care for this large and ill population.
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Hemodynamic Support in Management of Cardiogenic Shock
Observational studies suggest that a shock team approach is associated with higher PA catheter use, more appropriate MCS use (and paradoxically, a lower MCS use overall), and potentially lower mortality.
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Radiofrequency Ablation Offers a Nonsurgical Treatment for Thyroid Nodules
An ultrasound picture of the thyroid nodule, seen as an oval grey mass, sitting on top of the trachea (windpipe). It is surrounded by the anterior strap muscles, sternocleidomastoid muscle and common carotid artery.
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Peter O’Donnell Jr. Brain Institute - 2021-2022 Seminar Series
The O'Donnell Brain Institute seminar series will feature outstanding speakers to promote discovery and innovation in brain sciences. Held the 1st and 3rd Thursdays of each month.
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Single Protein Prompts Mature Brain Cells to Regenerate Multiple Cell Yypes Published on:
A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study. The findings might someday lead to a way to regenerate brain tissue after disease or injury.
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UTSW Study Finds It Safe to Give Clot-busting Drug to Stroke Patients Who Took Blood Thinners
Stroke patients on long-term blood thinners who were given the clot-busting drug alteplase enjoyed better recoveries than those who did not receive the drug and had no increased risk of bleeding, a new study led by UTSW researchers shows. The results run counter to the common practice of withholding the clot-busting drug to these patients due to concerns over complications from bleeding.
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UTSW Researchers Identify Key Complex for Ribosome Generation
UT Southwestern researchers have identified a four-protein complex that appears to play a key role in generating ribosomes – organelles that serve as protein factories for cells – as well as a surprising part in neurodevelopmental disorders. These findings, published in Cell Reports, could lead to new ways to manipulate ribosome production, which could impact a variety of conditions that affect human health.
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O'Donnell Brain Institute Becomes Hub for Cerebellar Ataxia Care and Research
UT Southwestern has expanded its Movement Disorders Clinic in the Peter O’Donnell Jr. Brain Institute to become a hub for research and care for patients with cerebellar ataxia, a disorder that causes uncoordinated movements and imbalance due to damage in a part of the brain called the cerebellum.
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UTSW Study Finds Cognitive Decline Key Factor in Predicting Life Expectancy in Alzheimer’s Disease
Using a National Alzheimer’s Coordinating Center dataset on 764 autopsy-confirmed cases, C. Munro Cullum, Ph.D., Professor of Psychiatry, Neurology, and Neurological Surgery, and first author Jeffrey Schaffert, Ph.D., a postdoctoral fellow in clinical neuropsychology at UT Southwestern, identified seven factors that helped predict life expectancy variances among participants. These factors are the most predictive of how many years of life remain after diagnosis.
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The ART and Science of Targeting Gynecologic Tumors
Adaptive radiation therapy (ART) – a new patient tumor personalized technology – is now available to treat and cure women with cervical cancer and other gynecologic tumors.
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Do Coronary Artery Calcium Scores Improve Risk Assessment for Individuals with Low Socioeconomic Status?
Do Coronary Artery Calcium Scores Improve Risk Assessment for Individuals with Low Socioeconomic Status?