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Updates in Multidisciplinary Treatment of Colorectal Cancer
Experts in surgery, medical oncology, and radiation oncology describe the benefits of a multimodal approach and identify novel treatment paradigms for colorectal cancer. Watch lectures, a case-based study, and Q&A with Simmons Cancer Center physicians.
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Lipid Nanoparticles Carry Gene-Editing Cancer Drugs Past Tumor Defenses
As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult. Now, scientists at UT Southwestern have developed nanoparticles that can break down the physical barriers around tumors to reach cancer cells. Once inside, the nanoparticles release their payload: a gene editing system that alters DNA inside the tumor, blocking its growth and activating the immune system.
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UTSW Researchers Develop Blood Test to Predict Liver Cancer Risk
Protein levels in blood samples of patients with nonalcoholic fatty liver disease reveal those at highest risk who should be screened regularly for liver cancer. Now, UT Southwestern researchers have developed a simple blood test to predict which NAFLD patients are most likely to develop liver cancer.
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First Successful Mini-Thoracotomy Bentall Using KONECT Valve
Cardiothoracic surgeon Neelan Doolabh, M.D., has performed more than 3,000 mini-thoracotomy cardiac surgeries through a two-inch intercostal incision. Now, Doolabh has achieved something even more challenging, performing a full bio-Bentall procedure using the same minimally invasive approach.
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An Innovator at the Helm: Chair of Radiation Oncology Plans Big Changes
"Tumors constantly evolve, and that evolution creates opportunities for cancer to elude the ongoing therapy. No single strategy will work. We must have a treatment to uniquely fit the particular patient’s situation." -Robert Timmerman, M.D., Chair of Radiation Oncology
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Telemedicine, Continuous Glucose Monitoring Mitigated Effects of Pandemic on Children with Diabetes
The rapid adoption of telemedicine and increased use of continuous glucose monitoring helped to attenuate the impacts of the COVID-19 pandemic on children with Type 1 diabetes, according to a new study from UT Southwestern researchers.
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Leadership Q&A with Dr. J. William Harbour
J. William Harbour, M.D., joined UT Southwestern in November 2021 as the new Chair of Ophthalmology.
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Minimally Invasive Heart Valve Surgery: Aortic Valve Replacement
Through a small two-inch incision and without cutting the breastbone, Dr. Neelan Doolabh performs a minimally invasive aortic valve replacement surgery at Clements University Hospital.
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DOACs for LV Thrombus: The Experience from a Safety Net Hospital
An uncommon but potentially devastating complication of a cardiomyopathy is the formation of a left ventricular (LV) thrombus that embolizes and causes end-organ damage such as a stroke.
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A Blurred Line: What’s the Distinction Between Primary and Secondary Prevention Today?
In an era of increasing use of coronary artery calcium (CAC) scanning, where asymptomatic individuals with high burdens of atherosclerosis are detected, what is the distinction between primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD)? That was the topic of a joint session between the American Society for Preventive Cardiology and AHA that I moderated at #AHA21.
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Researchers Use Machine Learning to Identify Autism Blood Biomarkers
Using machine learning tools to analyze hundreds of proteins, UT Southwestern researchers have identified a group of biomarkers in blood that could lead to an earlier diagnosis of children with autism spectrum disorder (ASD) and, in turn, more effective therapies sooner.
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Using Machine Learning to Predict Pediatric Brain Injury
UT Southwestern scientists have shown that a machine learning program can predict, more accurately than doctors, which babies and children are most likely to suffer brain injury after ECMO.