Search Videos and More
News
Fluorescent nanoprobe lights the way to reducing spread of cancer cells
Healthy cells “eat” glucose, or sugar, to gain energy, divide, and heal themselves. Cancer cells, by comparison, consume glucose at a much higher volume to change their makeup, grow, and spread. The resulting byproduct is a tumor that secretes high levels of lactic acid, crippling the immune system’s defenses against the cancer.
News
Using nanotechnology to attack cancer’s Achilles’ heel: acidity
Although cancers come in many forms, they all have a lower pH than normal tissue. Pharmacologist Jinming Gao, Ph.D., and head and neck surgeon Baran Sumer, M.D., have been working together for years on a pH-sensitive technology that can help surgeons more precisely excise tumors and help anti-tumor drugs get exactly where they need to be.
News
Illuminating cancer: New pH threshold sensor improves cancer surgery
The high acidity of cancer cells yielded the clue that led to the development of a tool that significantly improves surgeons’ abilities to remove cancerous tissues. The invention by UT Southwestern researchers is a transistor-like threshold sensor that hones in on high pH, literally lighting up cancerous cells.
News
UT Southwestern researchers seek to light up cancer cells so surgeons can better see where to cut
Baran Sumer, M.D. Professor and Chief of the Division of Head and Neck Oncology in UT Southwestern’s Department of Otolaryngology and a team of researchers from the Simmons Comprehensive Cancer Center developed a technology called a pH Nanosensor, an injection that seeks out cancerous areas in the body and causes them to light up.
News
A transistor-like pH nanoprobe for tumour detection and image-guided surgery
UT Southwestern’s Baran Sumer, M.D., Professor and Chief of the Division of Head and Neck Oncology in the Department of Otolaryngology is among other researchers to report the design and performance of a fluorescent nanoprobe with transistor-like responses (transition pH?=?6.9) for the detection of deregulated pH, which drives many of the invasive properties of cancer.
News
Gut microbiome offers clues to disparities in rectal cancer
UT Southwestern study identifies clustering of specific gut bacteria associated with race, ethnicity in patients
Video
Cancer Researchers are “Lighting Up” Cancer
Learn how cancer researchers are “lighting up” cancer by watching our Facebook Live chat with otolaryngologist Baran Sumer, M.D. Dr. Sumer is part of a team that developed a transistor-like nanosensor that can illuminate cancerous cells to assist surgeons.
Video
Factors Associated with Lymph Node Count in Head and Neck Cancer
Surgeons from the University of Texas Southwestern Medical Center carried-out a retrospective study on 247 patients with head and neck cancer to test whether age and undernutrition, factors known to negatively affect immune function, decreased lymph-node count in patients undergoing neck dissection.
News
Nanoparticles developed at UTSW effectively fight tumors
Activating a specific pathway in a subset of immune cells eradicates immunologically ‘cold’ tumors, UTSW study shows
News
How Glen’s journey to getting a power wheelchair got much smoother
Glen Denehie is a substitute teacher, soccer fanatic, home cook, and dad of two busy teens. He also has facioscapulohumeral muscular dystrophy (FSHD), one of 30 forms of muscular dystrophy.
News
Ethnic minorities face higher risk of liver transplant failure
UTSW study of patients with alcohol-associated diseases could lead to interventions that improve outcomes of these procedures
News
Lung cancer treatment shows promise in tumor models
UT Southwestern study uses 6-thio-dG molecule to damage DNA and halt spread of small cell lung cancer