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UT Southwestern scientists discover agent that reverses effects of intoxication
A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn’t receive this treatment, UT Southwestern researchers report in a new study.
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Inflammation Linked to Insulin Resistance and Fatty Liver Disease
UT Southwestern researchers demonstrate that in obesity, activation of antiviral pathways link inflammation to nonalcoholic fatty liver disease (NAFLD) and dysglycemia.
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Inappropriate Forceps Use in Polypectomy: Common but Modifiable
Our research showed that while snare polypectomy is more effective at complete resection of non-diminutive polyps, cold forceps are used to remove these polyps in more than 20% of colonoscopies, increasing the risk of incomplete resection. Inappropriate forceps use can be modified with interventions to prevent more post-colonoscopy cancers.
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Suboptimal Ultrasound Visualization Impacts Accuracy of HCC Screening in Patients with Cirrhosis
UT Southwestern researchers have found that suboptimal visualization reduces the effectiveness of ultrasound screening to detect hepatocellular carcinoma (HCC) at an early stage in patients with cirrhosis. These data suggest that patients with suboptimal ultrasound visualization would likely benefit from alternative screening methods.
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Novel Blood Test to Assess Liver Cancer Risk in Patients with NAFLD
UT Southwestern researchers have developed a blood test that can predict long-term risk of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease (NAFLD). The test was particularly effective at identifying patients at low risk, suggesting they may not need to be observed and monitored as closely as high-risk patients.
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UTSW Researchers Discover New Drug Target for Inflammatory Bowel Disease
A set of interacting molecules in immune cells of the gut is responsible for preventing the inflammation seen in inflammatory bowel diseases (IBD), UT Southwestern researchers report in a new study. The findings, published in Cell Reports, suggest a new drug target for treating IBD and related conditions.
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Behind the Scenes: SSO Robotic Surgery Pre-Meeting
Step behind the scenes at UT Southwestern’s Robotic Surgery Symposium at the Society of Surgical Oncology 2022 meeting in Dallas, Texas
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Research into Cachexia Seeks Treatment for Muscle-wasting Condition
Dr. Infante’s research group has identified several influential molecules that are secreted from tumors or their associated inflammation.
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Happiness Might Protect You from Gastrointestinal Distress!
Serotonin, a chemical known for its role in producing feelings of well-being and happiness in the brain, can reduce the ability of some intestinal pathogens to cause deadly infections, new research by UT Southwestern scientists suggests.
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Stomach Issues, History of Substance Abuse Found in Teen Vaping Study
A study of teens diagnosed with the vaping-linked respiratory disease EVALI revealed that most also had gastrointestinal symptoms and a history of psychosocial factors, including substance abuse, UT Southwestern researchers found in one of the first clinical reviews of its kind.
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Fighting Inflammatory Bowel Disease at Its Source
New findings on mechanism for intestinal inflammation could offer new targets for treating ulcerative colitis, Crohn’s disease, and other conditions