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How an experimental drug reverses fatty liver disease
Promising treatment in clinical trials has double action against triglyceride and fatty acid synthesis, UTSW study shows
Video
Inside the OR: Robotic Pancreatic Surgery
The Whipple procedure is one of the most technically challenging abdominal surgeries – and it is also a UT Southwestern specialty. In this video, Dr. Herbert Zeh, Chair of our Department of Surgery, and Dr. Patricio Polanco, a GI and robotic surgery expert, take you inside the operating room for a firsthand look at this complex surgery.
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Personalized approach suggested on colorectal cancer screening
Conventional age-based guidelines for screening do not account for health status, life expectancy, UT Southwestern researchers find
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UTSW researcher receives NIH Director’s New Innovator Award
Funding will spur gastroenterologist’s investigation into how tumor location affects outcomes in cancer cases
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UTSW researchers identify driver of inflammatory bowel disease
Researchers at UT Southwestern Medical Center have discovered an intracellular mechanism that converts protective intestinal cells into disease-driving pathogenic cells, a finding that could lead to improved treatments for patients with inflammatory bowel disease (IBD).
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Tumor loss-of-function mutations in STK11/LKB1 induce cachexia
Cancer cachexia (CC), a wasting syndrome of muscle and adipose tissue resulting in weight loss, is observed in 50% of patients with solid tumors. Management of CC is limited by the absence of biomarkers and knowledge of molecules that drive its phenotype.
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UT Southwestern: A global leader in robotic pancreas surgery
Traditionally performed through a large incision, at UT Southwestern our pancreatic cancer surgeons have specialized in robotic-assisted Whipple surgery, a more precise approach through smaller incisions that has been proven to benefit patients with faster recovery times, less pain, less use of pain medication, and prompter return to work. It has also been shown to have comparable cancer treatment results with lower rates of complications and transfusions than the open surgery.
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UT Southwestern scientists discover agent that reverses effects of intoxication
A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn’t receive this treatment, UT Southwestern researchers report in a new study.
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Inflammation Linked to Insulin Resistance and Fatty Liver Disease
UT Southwestern researchers demonstrate that in obesity, activation of antiviral pathways link inflammation to nonalcoholic fatty liver disease (NAFLD) and dysglycemia.
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Inappropriate Forceps Use in Polypectomy: Common but Modifiable
Our research showed that while snare polypectomy is more effective at complete resection of non-diminutive polyps, cold forceps are used to remove these polyps in more than 20% of colonoscopies, increasing the risk of incomplete resection. Inappropriate forceps use can be modified with interventions to prevent more post-colonoscopy cancers.
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Suboptimal Ultrasound Visualization Impacts Accuracy of HCC Screening in Patients with Cirrhosis
UT Southwestern researchers have found that suboptimal visualization reduces the effectiveness of ultrasound screening to detect hepatocellular carcinoma (HCC) at an early stage in patients with cirrhosis. These data suggest that patients with suboptimal ultrasound visualization would likely benefit from alternative screening methods.
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Novel Blood Test to Assess Liver Cancer Risk in Patients with NAFLD
UT Southwestern researchers have developed a blood test that can predict long-term risk of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease (NAFLD). The test was particularly effective at identifying patients at low risk, suggesting they may not need to be observed and monitored as closely as high-risk patients.